The fresh new overlying epithelium are hyperplastic parakeratotic stratified squamous epithelium showing numerous elongated rete ridges
The fresh new overlying epithelium are hyperplastic parakeratotic stratified squamous epithelium showing numerous elongated rete ridges


Inside the oral cavity periodontium can show different kinds of focal overgrowths. This type of lesions happen on account of overgrowth and you can expansion of different parts regarding connective structure when you look at the periodontium, we.elizabeth. new materials, bone, cementum, blood-vessel otherwise one types of type of phone. This new lexicon out-of focal proliferative sores commonly taking place toward gingival structure is sold with fibroma, icon cellphone fibroma, pyogenic granuloma, peripheral large phone granuloma, POF and you can POdF. A few of these sores is actually reactive persistent inflammatory hyperplasias, having small upheaval or persistent annoyances being the etiologic things.

The fresh new nomenclature ones lesions is completed in a way in order to focus on the difference in the wild from growth, venue of development, provider and also the principal proliferating histological role/tissue regarding lesion. This new sores that are present intraosseously try known as “main lesions”, whereas their extraosseous alternatives or the sores and therefore appear on external delicate muscle (elizabeth.g. gingiva) is actually called “peripheral lesions”. Along with, an excellent lesion mation on account of a stimulation that's known as a “reactive lesion” otherwise it could be it is “neoplastic” where it’s categorized due to the fact an ordinary or a cancerous neoplasm.

The new POF, symbolizing an activated benign lesion regarding conjunctive structure, is not necessarily the softer tissue similar (or relevant anyway) in order to main ossifying fibroma hence signifies a keen osteogenic neoplasm

The term POF is coined of the Eversole and you can Robin. It occurs entirely on gingiva. It’s a comparatively preferred development of gingiva that's experienced to get reactive in nature in lieu of neoplastic. POF try characterized by a high standard of cellularity usually exhibiting bone creation, in the event sporadically, cementum-such as for example material or dystrophic calcification can certainly be receive.

As lesion takes place merely toward gingiva which will be supposed to be based on periodontal ligaments, certain regulators thought new lesion getting odontogenic from inside the provider.

At this time, the foundation and you will pathogenesis of your lesion is actually unknown. not, making use of their systematic and you can histopathologic resemblance, it’s considered that no less than some instances of POF can get arise down seriously to growth from an extended-condition pyogenic granuloma.

The fresh new POF has a highest incidence inside the younger and you can teenaged ladies. Cundiff reported that brand new lesion was prevalent ranging from chronilogical age of 5 and you can 25 years, that have a maximum frequency within thirteen years of age. Cundiff along with said a definite women predilection. Women to help you men ratio may vary regarding 2:step one to three:2. This site away from occurrence out-of POF is normally anterior to molars both in maxilla and mandible similarly, and in over 50% of circumstances on the incisor, and you will cuspid places.

Clinically, brand new lesion looks like a good nodular mass which can be pedunculated or sessile, red to help you purple when you look at the colour and you will surface can be although not usually ulcerated. In the present case and additionally, the newest lesion took place a middle-old females during the mandibular anterior area and you will seemed due to the fact an effective nodular pale so you're able to red growth instead of ulceration.

Histopathologically, the lesion suggests stratified squamous epithelium coating an extremely cellular bulk off conjunctive structure comprised of fat fibroblasts, fibrocytes, fibrillar stroma and aspects of mineralization having multinucleated giant structure near him or her sometimes. The mineralization can get feature limbs, cementum-such as topic or dystrophic calcifications. The brand new dystrophic calcifications are usually seen in very early, ulcerated lesions, while the newest older, adult, non-ulcerated sores inform you well-molded limbs and you may cementum-for example issue, since the is actually obvious in the present instance in addition to.

The logical differential prognosis from POF boasts all the nodular sores and this are present with the gingiva (as previously mentioned just before). Histopathologically, it is very important to learn the difference between the similar sounding lesions, we.e. POF, POdF, main ossifying fibroma (COF) and you will main odontogenic fibroma (COdF).